Peptides

CJC-1295 WITH DAC 12.5MG

$100.00

Purity 99.07% / Avg. mass 13.05 mg

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Discreet packaging
In stock

01 — Description

What it is

CJC-1295 With DAC is a long-acting synthetic analogue of the biologically active 29-amino-acid region of human growth hormone-releasing hormone, or GHRH. Its Drug Affinity Complex, known as DAC, allows the peptide to bind to circulating albumin, extending its presence in the bloodstream compared with shorter-acting GHRH analogues.

Studied Uses

CJC-1295 With DAC has been investigated in clinical and preclinical research involving:

Pituitary growth-hormone secretion
GHRH-receptor activity
Insulin-like growth factor 1, or IGF-1, production
Long-acting GHRH analogue pharmacokinetics
Preservation of pulsatile growth-hormone signalling
Hormonal responses following single and repeated administration

Human studies in healthy adults found that CJC-1295 produced sustained, dose-dependent increases in circulating growth hormone and IGF-1. Separate research found that growth-hormone pulsatility remained present while mean and trough GH levels increased.

How It Works

CJC-1295 binds to GHRH receptors on somatotroph cells in the anterior pituitary gland. This stimulates the synthesis and release of endogenous growth hormone, which subsequently increases IGF-1 production in the liver and other responsive tissues.

The DAC modification enables the peptide to form a long-lasting association with serum albumin. This reduces rapid clearance and enzymatic breakdown, resulting in more prolonged stimulation of the GH–IGF-1 signalling pathway than native GHRH or No-DAC analogues.

Product Details

Product: CJC-1295 With DAC
Strength: 12.5 mg
Form: Lyophilized powder
Presentation: Single vial

02 — Details