Selank is a synthetic heptapeptide with the amino-acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It was developed from tuftsin, a naturally occurring immune-regulatory peptide, and has been investigated for its effects on anxiety-related behaviour, cognition, stress responses and neuroimmune signalling.
Studied Uses
Selank has been examined in research involving:
- Anxiety and stress-related responses
- Generalized anxiety disorder and neurasthenia
- Learning, memory and cognitive performance
- GABAergic and monoamine neurotransmission
- Brain-derived neurotrophic factor, or BDNF, expression
- Inflammatory and immune-response signalling
Small comparative human studies have investigated Selank in people with anxiety-spectrum conditions. Laboratory and animal studies have additionally examined its effects on learning, memory, stress-related behaviour, neurotransmitter systems and immune-associated gene expression.
How It Works
Experimental evidence suggests that it may influence GABA-related neurotransmission, including the interaction of GABA with GABA-A receptors and the expression of genes involved in neuronal signalling.
Research has also associated Selank with changes in serotonin and other monoamine systems, as well as regulation of BDNF expression in brain regions involved in learning, memory and stress responses. Its effects may therefore involve several interacting neurological and immune-signalling pathways.
The available evidence includes small human studies and substantial preclinical research.
Product Details
Product: Selank
Strength: 12.5 mg
Form: Lyophilized powder
Presentation: Single vial
Reviews
There are no reviews yet.